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My dog's UTI is resistant to antibiotics. What are treatment options?

Updated On September 23rd, 2025

Pet's info: Dog | Beagle | Male | unneutered | 5 years and 2 months old | 31 lbs

MY 5 YEAR OLD MALE BEAGLE HAS UTI & CULTURE REPORT IS SEMI QUANTITATIVE >10/7 BACTERIA/ML OF URINE QUALITATIVE BACILLUS SPP RESISTANT TO ALL AVAILABLE ANTIBIOTICS WHAT TREATMENT TO BE TAKEN? WHAT DOES IT MEAN?

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1 Answer

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Answered By Daniel Fonza, DVM

Veterinarian

Published on February 23rd, 2018

Hi there and thank you for using Petco Pet Education Center, formerly Petcoach to address your concern. I am sorry to hear that Scotch is dealing with such a severe urinary tract infection! Unfortunately this is going to be quite the difficult case to manage due to such the resistance to antibiotics. In this case it would be worth trying a multi-antibiotic approach and you may need to resort to an antibiotic such as Amikacin, which can have adverse effects on the kidneys. Unfortunately, I see that Amikacin is also on the list of antibiotics that this is resistant to. There are more alternative methods of treatment such as ozone therapy in the bladder which may help kill the bacteria. I would discuss this further with your veterinarian as treatment will depend entirely on what the vet wants to use. Scotch may need to be admitted into the hospital for treatment for IV antibiotics as well. I hope this helps guide you in the right direction. Please let me know if you have any other questions or concerns and I would be more than happy to help you further.

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