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My dog's Piriton isn't working. Are other antihistamines better?

Updated On September 23rd, 2025

Pet's info: Dog | Pug | Female | spayed | 7 years and 4 months old | 14.5 lbs

Hi do all anthistamines work the same ? Looking them up online they seem to have different ingredients different bases My dog takes piriton twice daily but hand on heart I'm unsure if it's doing anything so would another brand be different or not ?

1 Answer

Most Helpful Answer

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Answered By Jennifer Summerfield, DVM CPDT-KA

Veterinarian, Certified Dog Trainer

Published on February 19th, 2018

In general, antihistamines are not very effective in dogs for itching - so unfortunately, it doesn't surprise me that you aren't seeing much effect with Piriton. You could certainly talk to Lily's veterinarian about trying a different antihistamine such as hydroxizine or diphenhydramine, as some dogs may respond a bit better to a different drug.

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