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Is Pepcid safe for dogs with kidney failure, despite human warnings?

Updated On September 23rd, 2025

Pet's info: Dog | Chihuahua | Male | neutered | 14 years old | 5.4 lbs

Hi. My dog is in Kidney failure and his vet gave him Pepcid. But, I read on the package that people with kidney disease should not take it. Would this be different for dogs?

3 Answers

Most Helpful Answer

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Answered By Jennifer Summerfield, DVM CPDT-KA

Veterinarian, Certified Dog Trainer

Published on February 16th, 2018

Hi there! I'm not sure what the reasoning is on avoiding it with kidney disease in humans, but I can tell you that it's used extremely commonly in dogs with chronic kidney disease without any problems. It's a very safe drug in general, and can often be helpful for patients with this problem because kidney failure can cause excessive acid production in the stomach. The Pepcid helps with this.

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15Pet Parents found this answer helpful

Other Answers

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    Answered By Angel Alvarado, LVT

    Licensed Veterinary Technician

    Published on September 21st, 2018

    Pepcid (famotidine) can be used safely in cats. Discuss a safe dose, based on Mocha's weight, with your veterinarian. If you give it in pill form, be sure to offer a drink afterwards to wash it down. Famotidine is most effective when given on an empty stomach.

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    1Pet Parents found this answer helpful

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    Answered By Laura Johnson VMD

    Veterinarian

    Published on February 12th, 2018

    Hi, thanks for using Petco Pet Education Center, formerly Petcoach! It is common to use Pepcid in animals in kidney failure. I would discuss dosing with your Vet. I would also ask for anti-nausea medications like reglan or cerenia. Pepcid is just an antacid. I hope this helps!

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