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My senior dog's high ALP and thirst: What do blood tests mean?

Updated On September 23rd, 2025

Pet's info: Dog | English Setter | Female | spayed | 14 years and 7 months old | 66 lbs

Hi pleas can you help me with my dogs blood count I do not understand the results it says bun 43 glu 1.02 alp 1500 t-pro 66 gpt283 cre 18 t-cho 4 I am English but this test of blood was done in France they gave me nothing I do not think this test is normal especially the alp 1500 Lola has increase thirst panto g and walking around the house a lot she is nearly 15 so a opp is out the question she can not have a lot of meds because her liver is enlarged she is a English setter thank you please hel

1 Answer

Most Helpful Answer

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Answered By Daniel Fonza, DVM

Veterinarian

Published on February 16th, 2018

Hi there and thank you for using pet coach to address your concern. The ALP is quite high but this also depends on their reference ranges there. The symptoms you are describing could be consistent with a condition called hyperadrenocorticism (Cushing's disease) which is when there is excessive steroid production in the body due to a pituitary tumor or adrenal gland mass. There is treatment for the disease but it needs to be confirmed first. If you want to know for sure, testing such as an ACTH or low dose dexamethasone test should be performed. You can try using melatonin and flaxseed lignans to treat cushings disease naturally. I have had some cases respond to this treatment but not 100%. Also, I see that cre is 18. If this is creatinine, this is very high. Again, this depends on the machines reference range, calibration and unit of measure. Creatinine elevates typically with renal disease, which could also explain the increased thirst. If you attach a picture and repost to the forum here, it may help us better guide you. I hope this helps! You can visit a website called lignansforlife.net and order the holistic medications that I spoke of earlier. Please let me know if you have any other questions or concerns and I would be more than happy to help you further.

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