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My dog accidentally got double tramadol & amitriptyline. What now?

Updated On September 23rd, 2025

Pet's info: Dog | English Bulldog | Male | neutered | 10 years and 10 months old | 90 lbs

My 11 year old English Bulldog was accidentally fed and medicated. 2x in one hour. He was given 150 mg of tramadol total snd 50mg of amitriptyline - what should I do?

2 Answers

Most Helpful Answer

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Answered By Kevin Sanada, DVM

Veterinarian

Published on February 13th, 2018

Alone, these drugs would not be too concerning for a 2x overdose, but the combination is more dangerous to overdose. The combination can cause significant problems with the neurotransmitters in the brain and lead to life-threatening heart problems, breathing problems and seizures. This is not a big overdose, so I can't say that these problems will occur, but it is definitely possible. For this reason, it's best to take him to a vet right away. The vet can take steps to keep the medication from being absorbed and give the necessary medication to keep Oscar safe from potential adverse effects. I hope that helps and all is well with Oscar.

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Other Answers

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    Answered By Dr. Heidi DVM, CVA, CCRT, CVTP, CVSMT, CVCH

    Veterinarian, Certified Veterinary Acupuncturist, Certified Canine Rehabilitation Practitioner

    Published on

    We have all done this, so don't beat yourself up. Tramadol has a fairly large dosage range, so Oscar may be more tired or lethargic with a double dose, but I would not expect any other problems with a double dose of Tramadol. It looks like Oscar is on a lower dose of Amitriptyline, so even with a double dose he is still within a normal dosage range. My only concern is that Tramadol and Amitripyline can interact with each other, so I would recommend contacting your veterinarian tomorrow for a recommendation on Oscar's medication dosing tomorrow in case they recommend a lower dose tomorrow. If Oscar seems agitated, has diarrhea or develops any muscle tremors, I would have him evaluated right away. Good luck! I hope that was helpful and that Oscar will be fine. Thanks for using Petco Pet Education Center, formerly Petcoach.

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