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Why is my dog lethargic and shaking after getting his shots today?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | 1 year and 9 months old | 70 lbs

Pitbull got Imrab 3 TF and DApp today. He is lethargic and shaking like he is cold. Should I be worried?

2 Answers

Most Helpful Answer

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Answered By Ricardo Fernandez, DVM

Veterinarian, Veterinary Oncology Resident

Published on February 5th, 2018

Thanks for using Petco Pet Education Center, formerly Petcoach! Possible side effects after vaccines include pain at the injection site, lethargy, inappetence and general discomfort. This should subside within 1-2 days. If it does not improve or it worsens, have Boomer evaluated by a veterinarian for further assessment and treatment. Otherwise, Boomer will likely start feeling better shortly. Good luck and best wishes!

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    Answered By Angel Alvarado, LVT

    Licensed Veterinary Technician

    Published on February 28th, 2019

    This can happen after vaccines. If it lasts longer than 24 hours, have her rechecked by your veterinarian. Monitor for vomiting, diarrhea, difficulty breathing or any swelling. These can indicate a vaccine reaction and should be addressed immediately by your veterinarian or at the nearest veterinary ER.

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