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My dog has Lyme disease. Is Nexgard safe? Can he get re-infected?

Updated On September 23rd, 2025

Pet's info: Dog | Border Collie | Male | neutered | 3 years and 1 month old | 54 lbs

My dog has tested positive for Lyme disease has come in contact with a infected tick, further blood/urine test is on going. My question is can taking Nexgard complicate his condition further? If his own antibodies have fought off the disease the first time will this not occur should he be exposed to it in the future? Thank you Jeff

1 Answer

Most Helpful Answer

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Answered By Laura Johnson VMD

Veterinarian

Published on January 10th, 2018

Hi, thanks for using Petco Pet Education Center, formerly Petcoach! If Tyson has Lyme disease he should be put on a good flea and tick medication like Nexgard year round. Plus ticks carry many other diseases besides Lyme disease. Once he is healthy I would also consider vaccinating him for Lyme. Dogs can get re-infected with Lyme disease despite being exposed previously. I would also check urine samples twice yearly for the development of protein in his urine. Protein in the urine can be an indicator of Lyme nephropathy which is a devastating kidney disease from Lyme. Not all dogs get this secondary complication. I hope this helps and I wish Tyson the best!

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