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My dog needs Deramaxx. How safe is it and what side effects should I watch for?

Updated On September 23rd, 2025

Pet's info: Dog | Pembroke Welsh Corgi | Male | neutered | 16 years and 8 months old | 27 lbs

My vet prescribed Deramaxx for my dog who has been panting and trying to reach his back side for unknown reasons. This is to rule out (or in) if there is any pains that are causing him to act this way. I came across some horror stories of dogs dying from internal bleeding from this medicine and I am terrified. My vet didn't do blood test, but there is no reason to believe my dog has weak kidney or liver. So is Deramaxx considered as a safe medicine? or no? I am terrified of the bad reaction.

1 Answer

Most Helpful Answer

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Answered By Destini R. Holloway, DVM

Veterinarian

Published on January 4th, 2018

I can understand your concerns. Deramaxx, just like any other pet formulated NSAID, has the potential to cause adverse reactions in dogs. There is no medicine for suspected osteoarthritis that is considered 100% free of possible side effects in dogs. With that said, you should be informed on the potential side effects and what symptoms to watch out for that could indicate there is a problem, such as vomiting, lethargy, decreased appetite, loose stool with or without blood, and to notify your vet if any are seen. For long term use, it is advised to have baseline bloodwork done on your pet to rule out any underlying kidney or liver problems as well. And if your pets history of health is unclear or unknown to your vet, bloodwork should even be considered before the first dose is given. But pets are prescribed this medicine all the time with little to no side effects; although that perspective can be skewed when owners only list the bad outcomes via the internet. However if you do see unwanted side effects it’s recommended to notify your vet immediately and stop the medication. However, there is a good chance he will do well. Best wishes and take care.

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