Updated On September 23rd, 2025
Pet's info: Dog | Mixed Breed Large (61lb +) | Female | spayed | 56.8 lbs
What’s the difference in cephalexin and simplicef
1 Answer
Published on December 27th, 2017
Cephalexin and Simplicef are both cephalosporins, so they are the same group of antibiotics, but cephalexin is the generic name for a 1st generation cephalosporin and Simplicef is a trade name for Cefpodoxime which is a 3rd generation cephalosporin (so it is a newer drug) and works better in some circumstances. Here is more information on both drugs. https://www.veterinarypartner.com/Content.plx?P=A&S=0&C=0&A=538 https://www.veterinarypartner.com/Content.plx?P=A&S=0&C=0&A=2038 I hope that was helpful! Thanks for using PetCoach.
5Pet Parents found this answer helpful
Book an appointment with the pros – our expert vets are here to help.