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My dog is out of Zyrtec. Can I give him Xyzal, and what's the dose?

Updated On September 23rd, 2025

Pet's info: Dog | Pit Bull Terrier | Male | neutered | 70 lbs

my dog is 70 lbs, male pitbull, neutered 5 yr old. he was taking Zyrtec but i’m out. is it safe to give him Xyzal? he was taking 1 Zyrtec a day. if Xyzal is safe for him would the dose be the same?

2 Answers

Most Helpful Answer

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Answered By Kevin Sanada, DVM

Veterinarian

Published on December 16th, 2017

Both drugs are used off-label - meaning that they are not approved for veterinary use, so it's important to only use them as recommended by your veterinarian. Xyzal has a similar drug to Zyrtec, but is different enough that a new dose would have to be calculated by your veterinarian. This drug also has a lack of safety information for use with dogs, so I would not recommend it. I hope that helps and all is well with Mo.

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    Answered By Dr. Melanie, BVSc MS

    Veterinarian

    Published on September 16th, 2017

    While most OTC antihistamines can be used in dogs, you should never give any medications to your dog without being prescribed by a vet. Unfortunately, by law it is illegal for the experts at Petco Pet Education Center, formerly Petcoach to give the dose information for any drug, including OTC drugs, without seeing the animal in person first. That's because doing so requires a veterinary client patient relationship which cannot be achieved via an internet forum. In addition, the experts cannot say for certain if a specific drug is safe for your dog. I would speak with your vet to see if they feel giving Zahavah xyzal is safe, and they can give you the appropriate dose.

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