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How reliable is the VDI-TK test for cat lymphoma? False results?

Updated On September 23rd, 2025

Pet's info: Cat | Siamese | Male | neutered | 8 lbs

Is the VDI-TK test reliable for testing feline intestinal lymphoma? Is there a high likelihood of false-positive or false negative result from the test? Thank you for answering the question.

2 Answers

Most Helpful Answer

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Answered By Dr. Strydom, DVM

Veterinarian

Published on December 10th, 2017

The VDI-TK test has a sensitivity of 0.78 and a specificity of 0.91 (High Positive Specificity >0.98) A highly sensitive test means that there are few false negative results, and thus fewer cases of disease are missed. The specificity of a test is its ability to designate an individual who does not have a disease as negative. A highly specific test means that there are few false positive results. Based on that, I would say that it is a reliable testing method for feline lymphoma. Here is a link about this testing that may answer more of your questions: http://vdilab.com/pdf/25_TKfelineTechSheet.pdf Hope this helps. Best wishes.

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    Answered By Elva Ma DVM

    Veterinarian

    Published on December 18th, 2017

    Hello, and thank you for your question. I looked into this topic for you. The general consensus among specialists at this time is that the VDI-TK test is still an unproven method of screening for lymphoma in all species, including cats. The few oncologists who routinely use this test primarily do it once lymphoma has been diagnosed by traditional methods, as part of monitoring response and remission status. To properly diagnose feline lymphoma versus IBD, the best method still lies with blood testing, ultrasound, exploratory and biopsy. I hope this helps!

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