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Why is my senior cat not eating, losing weight, and very lethargic?

Updated On September 23rd, 2025

Pet's info: Cat | American Shorthair | Female | spayed | 14 years and 10 months old | 7.5 lbs

14 yr old cat with weight loss, no appetite for food or water, very mildly elevated gall bladder/liver enzymes, excessive sleep.

1 Answer

Most Helpful Answer

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Answered By Dr. Melanie, BVSc MS

Veterinarian

Published on November 25th, 2017

Poor Piaf sounds very ill at the moment! It's quite concerning that she has no appetite for food and water, and this can quickly lead to a fatty liver (which cats develop when they don't eat for more than 72 hours) and dehydration. A fatty liver is fatal without treatment, so it needs to be avoided. It sounds like you have had some blood work done if she has very mildly elevated liver enzymes, but there may be something more going on with her such as cancer, which sometimes doesn't show up on blood work. I recommend further tests asap with the vet, such as x-rays and repeat blood work to start. She may also benefit from an appetitive stimulant and IV fluids to prevent dehydration. I would take her back into a vet immediately for treatment.

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