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My cat has GI fungus. Vet changed meds. Is this the right decision?

Updated On September 23rd, 2025

Pet's info: Cat | Ragdoll | Female | spayed | 13 years and 1 month old | 6.5 lbs

My cat has gastrointestinal candida. She's had it for a while and we've tried several medications. First Ketaconazole, but the cat spit it out without notice, it stopped working. Then itraconazole, but tried making solution from capsules - didn't work well, so gave direct from capsules. I have 10 more days of capsules, she's taken for 22 days. New fecal came back positive for fungus. The vet gave Grisulvin and said stop Itra capsules. Is this right? Why not finish Itra, and or use Nystatin?

2 Answers

Most Helpful Answer

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Answered By Mariya Gugel, DVM

Veterinarian

Published on November 24th, 2017

I'm sorry to hear that Azeara is not feeling well. All of the medications you mentioned are anti-fungals, and can be toxic in high doses. Your vet likely instructed you to stop one medication and switch to the other in order to avoid any chance of toxicity. You should definitely not give two of these medications at the same time unless instructed by your vet.

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    Answered By Christie Long, DVM

    Veterinarian, Certified Veterinary Acupuncturist

    Published on

    First, I’m sorry we weren’t able to answer your question in 30 minutes. Please know that you will not be charged for this answer because of it. I have so say that in 10 years as a small animal vet I have never treated GI candida and have always believed it to be a normal organism of the GI tract. If Azeara has diarrhea that is not responding to Antifungal treatments such as you have been giving then I suspect there is another cause and further diagnostics, such as a test for pancreatitis and cobalamin (vitamin B12) deficiency as well as an abdominal ultrasound should be considered.

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