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Why is my dog sick and lethargic after taking an antibiotic pill?

Updated On September 23rd, 2025

Pet's info: Dog | Yorkshire Terrier | Male | neutered | 5 years and 11 months old | 14 lbs

Hello, I was giving my yorkie his antibiotic pill and it got suck up under his lip so all the medicine went in his mouth and was bothering him a lot so I tried getting it out and rinsing his mouth but since then he's been acting sick and almost lethargic. Any help is appreciated, and I'm going to make an appointment tomorrow but I'm just wondering how this can make him so sick?

1 Answer

Most Helpful Answer

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Answered By Daniel Fonza, DVM

Veterinarian

Published on November 13th, 2017

Hello and thank you for your post! Speaking from personal experience, this used to happen to my dog as well. I would give him his capsule and sometimes it would get stuck under his lip and it would partially dissolve releasing the powder in his mouth. He would shake his head and foam at the mouth because of how bitter the powder was. He never got sick because of this and the powder generally will not cause any irritation it is just very bitter and distasteful. I would think that the antibiotic itself would be causing him to feel sick if he managed to swallow some of the antibiotic on an empty stomach. It is also possible that it has nothing to do with the medication that was administered and is completely something else that has led to him feeling sick. Since you have an appointment with your veterinarian, I would wait and see what the physical examination shows and possibly have Joel's blood tested. I hope this helps! Please let me know if you have any other questions and I would be more than happy to answer them for you.

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