My dog is lethargic from Gabapentin. Can I safely reduce the dosage?

Question

My dog, Labrador 40 kg, has osteosarcoma. He had been on Tramadol and Rimadyl for pain control but yesterday the vet recommended to add Gabapentin 900 mg once a day. Cautionsly, I gave him just 600 mg and he is completely lethargic. I'm afraid this dosage was too much. Can I reduce the dosage to 300mg for 1 day and then 100mg once a day (a more conservative dosage that may be increased according to respond). Pet's info: Dog | Labrador Retriever | Male | neutered | 10 years and 1 month old | 88 lbs

Laura Johnson VMD · Accepted Answer

Hi, thanks for using Petco Pet Education Center, formerly Petcoach! Poor Milo! Gabapentin can cause sedation alone and even more so with tramadol. My starting dose for Milo based on the weight you provided is 400mg every 12 hours. It is absolutely fine for you to go lower and increase the dose slowly based on Milo’s response. I hope this helps and I wish you and Milo the best!

My dog is lethargic from Gabapentin. Can I safely reduce the dosage?

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