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What can I give my dog for constant itching and suspected allergies?

Updated On September 23rd, 2025

Pet's info: Dog | Great Dane | Female | spayed | 110 lbs

We think our Great Dane has some sort of allergy, she will not stop itching all over her body and she has redness and welts on her mouth. We considered it to be atopy but we are not sure. Is there something we can use to help her with the constant itching?

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4 Answers

Most Helpful Answer

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Answered By Ricardo Fernandez, DVM

Veterinarian, Veterinary Oncology Resident

Published on November 7th, 2017

Thanks for using Petco Pet Education Center, formerly Petcoach! Medications like prednisone and Apoquel can help with the itchiness. The underlying allergy still has to be identified and treated. It really comes down to figuring out what is causing her allergies so that they can be treated or the specific allergen avoided. There are many things that can cause allergies though in most cases they can be broken down into 3 big categories: flea, food and environmental allergies. Allergies are usually worked up in a stepwise fashion starting with flea allergies as this is the easiest and cheapest to take care of. If not on a flea preventative, then it would be a good idea to get started on one. If already on one then it would be a good idea to change to something else (there are many new products out in the market). If not improved in 1-3 months then it is time to move on and check for food allergies by switching to a novel diet (new protein and new carbohydrate). If that does not seem to be the issue then you are left out having to check for environmental allergies which require blood and/or skin tests. Allergies can be very frustrating to deal with at first but so rewarding at the end when we are able to treat them effectively!

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2Pet Parents found this answer helpful

Related Answers from Veterinarians

  • Image profile

    Answered By Ricardo Fernandez, DVM

    Veterinarian, Veterinary Oncology Resident

    Published on November 29th, 2017

    Thanks for using Petco Pet Education Center, formerly Petcoach! While Benadryl may help temporarily it would just be for a very short amount of time and she will likely need further therapy. I agree that this is likely allergies but all of the possibilities in terms of allergies should be explored. Sometimes even if fleas are not seen, it can still be flea allergy as it only take one flea to cause allergies. It really comes down to figuring out what is causing her allergies so that they can be treated or the specific allergen avoided. There are many things that can cause allergies though in most cases they can be broken down into 3 big categories: flea, food and environmental allergies. Allergies are usually worked up in a stepwise fashion starting with flea allergies as this is the easiest and cheapest to take care of. If not on a flea preventative, then it would be a good idea to get started on one. If already on one then it would be a good idea to change to something else (there are many new products out in the market). If not improved in 1-3 months then it is time to move on and check for food allergies by switching to a novel diet (new protein and new carbohydrate). If that does not seem to be the issue then you are left out having to check for environmental allergies which require blood and/or skin tests. Allergies can be very frustrating to deal with at first but so rewarding at the end when we are able to treat them effectively!

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    1Pet Parents found this answer helpful

  • Image profile

    Answered By Ricardo Fernandez, DVM

    Veterinarian, Veterinary Oncology Resident

    Published on January 29th, 2018

    Thanks for using Petco Pet Education Center, formerly Petcoach! It is a bit hard to know without being able to see it though this is possibly due to allergies. It really comes down to figuring out what is causing her allergies so that they can be treated or the specific allergen avoided. There are many things that can cause allergies though in most cases they can be broken down into 3 big categories: flea, food and environmental allergies. Allergies are usually worked up in a stepwise fashion starting with flea allergies as this is the easiest and cheapest to take care of. If not on a flea preventative, then it would be a good idea to get started on one. If already on one then it would be a good idea to change to something else (there are many new products out in the market). If not improved in 1-3 months then it is time to move on and check for food allergies by switching to a novel diet (new protein and new carbohydrate). If that does not seem to be the issue then you are left out having to check for environmental allergies which require blood and/or skin tests. Allergies can be very frustrating to deal with at first but so rewarding at the end when we are able to treat them effectively!

    Vote icon

    1Pet Parents found this answer helpful

  • Image profile

    Answered By Ricardo Fernandez, DVM

    Veterinarian, Veterinary Oncology Resident

    Published on July 10th, 2019

    Thanks for using Petco Pet Education Center, formerly Petcoach! This is possibly due to allergies. It really comes down to figuring out what is causing her allergies so that they can be treated or the specific allergen avoided. A secondary infection is likely and also needs to be addressed.  There are medications such as Apoquel or prednisone which may help with the itch. 

There are many things that can cause allergies though in most cases they can be broken down into 3 big categories: flea, food and environmental allergies. 

Allergies are usually worked up in a stepwise fashion starting with flea allergies as this is the easiest and cheapest to take care of. If not on a flea preventative, then it would be a good idea to get started on one. If already on one then it would be a good idea to change to something else (there are many new products out in the market). 

If not improved in 1-3 months then it is time to move on and check for food allergies by switching to a novel diet (new protein and new carbohydrate). If that does not seem to be the issue then you are left out having to check for environmental allergies which require blood and/or skin tests.

 Allergies can be very frustrating to deal with at first but so rewarding at the end when we are able to treat them effectively!

    Vote icon

    1Pet Parents found this answer helpful

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