Why is my cat lethargic, not eating, and has high liver enzymes?

Question

I have a male cat that has had several issues with uti and crystals requiring surgery. Recently had a uti and finished a course of antibiotics 4 weeks ago. Vet appointment 1 week ago, lab results showed slightly elevate ALT and ALP. He had been put on a diet as well but vet said he’d lost too much weight- 4 lbs. he was given denamrin. 2 days in to taking led and he’s lost more weight, isn’t eating or drinking. He’s lethargic and just not himself. concerned it’s liver disease or kidney failure. Pet's info: Cat | Mixed Breed | Male | neutered | 8 years and 5 months old | 12 lbs

Rodrigo Roca, DVM · Accepted Answer

Hello, sorry to hear about Noa. Based on the information you provided, I would be most concerned with liver disease. This may require further diagnostics to rule out an infectious cause vs an inflammatory cause vs cancer. Most commonly in cats, we can see infectious and inflammatory causes for liver disease. Other diagnostics your veterinarian may offer is additional bloodwork, an abdominal ultrasound, and a biopsy of the liver. Hope this helps and best of luck!

Why is my cat lethargic, not eating, and has high liver enzymes?

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