Why are my dog's red, sore eyes and nose getting worse on Apoquel?

Question

My 6 year old male akita has extremely red sore eyes and nose my vet gave him apoquel tablets after a week of one tablet twice a day it seems to be getting worse not better, what could this be

Amber Da Silva, DVM · Accepted Answer

Based on the redness, crustiness and loss of pigment on the nose and eyelids, I would worry about him possibly having an auto-immune disease such as lupus or pemphigus. These diseases commonly affect the eyelids and nose in this way. Only a skin biopsy can definitively diagnose these conditions. It is also possible that there is a secondary infection. I would recommend having a skin cytology and a culture and sensitivity done. This means that the vet will take a superficial sample of those areas and look for bacteria. It will then be cultured to see what kind of bacteria is it and the sensitivity shows you what kind of antibiotic it is sensitive to. If there is an infection, it is best to clear that up prior to doing a biopsy as infection can make it hard to see the primary cause. Even though he doesn't seem to be responding to Apoquel, it could still be allergies. Most dogs I have treated with Apoquel have done very well, but there have been some dogs who don't improve in their allergy symptoms. I hope this helps and that he gets better soon!

Why are my dog's red, sore eyes and nose getting worse on Apoquel?

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