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How to help my African Clawed Frog: shedding, no appetite, lethargy?

Updated On September 23rd, 2025

Pet's info: Other | Unknown - Other | Female | unspayed

I have an African Clawed Frog who has been shedding her skin in tatters, has no appetite and can't keep down food. She is also very lethargic and I noticed this behavior on Tuesday. I know it has to do with poor water quality, since the new plants in the tank decayed very quickly and most likely bumped up the nitrates in the water. Right now I have her in quarantine with 1/2 tablespoon of aquarium salt in 1 gallon of water. The only medicine I have is tetracycline. Should I use it?

1 Answer

Most Helpful Answer

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Answered By Angel Alvarado, LVT

Licensed Veterinary Technician

Published on October 26th, 2017

Keep her in some clean water between 68 F and 77 F. Perform daily water changes using aged or conditioned water that is temperature matched to prevent further stress or shock. Clean water is the key to treating sick frogs. Aquarium salt is a great general tonic and can treat minor infection. Dissolve 1 tablespoon in 5 gallons of water and use that for water changes. You can add conditioners such as AmQuel and NovAqua as well as some StressCoat. She should begin to improve in a few days. Offer a few pellets daily, but remove them if she doesn't eat to prevent fouling the water.

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