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Is 100mg Trazodone too much for my 20lb puppy? What's the right dose?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | unspayed | 4 months and 9 days old | 20 lbs

Is 100 mg of Trazodone too much for a 20 lb puppy?

4 Answers

Most Helpful Answer

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Answered By Daniel Fonza, DVM

Veterinarian

Published on October 26th, 2017

Hi there and thank you for using Pet Coach. The dose for a 20lb puppy would be approximately 25mg every 12 hours with a max dose of 50mg. 100mg would be too high of a dose but would likely not cause significant problems. A dog with too high of a dose of Trazodone may exhibit sedation, lethargy and incoordination when walking. I hope this helps answer your question. Please let me know if you have any other questions or concerns. I am also available via consultation if needed.

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38Pet Parents found this answer helpful

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    Answered By Catherine Stecyk

    Veterinarian

    Published on March 20th, 2019

    Hello and thank you for reaching out to Petco Pet Education Center, formerly Petcoach. If your dog swallowed this amount, that is a very large dose for your dog. Normally we do not exceed 15 mg/kg, and that dose would be almost 23 mg/kg. If your dog ingested this within the last 2 hours, I recommend bringing him/her to your local veterinarian as soon as possible to have them induce vomiting. If it has been longer than that time, and you are unsure if he/she ate the pill, you can monitor for any changes in attitude. That amount of trazodone will likely make your dog very sleepy and sedated, so if you see any of these signs, he/she needs to be seen by a vet right away. I hope this is helpful!

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    10Pet Parents found this answer helpful

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    Answered By Lotus Altholtz

    Veterinarian, Board-Certified Lab Animal Medicine Specialist

    Published on February 18th, 2022

    That dose range is acceptable. The low end of dosing would be about 1.5 100 mg tablets for issues such as anxiety from fireworks, anxiety going to the vet’s, hyperactivity after a surgery where being calmer would be ideal. Unless your dog is super aggressive and the trazadone was prescribed prior to a visit for the safety of the veterinary staff, I would start with one 100 mg tablet and see how much of an effect it has on Ivy for the purpose indicated. If she doesn’t not seem appreciably calmer 30 min after the first tablet, you can give a second 30 min later.

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    Answered By Jeffrey Milner

    Veterinarian

    Published on September 20th, 2017

    HI, I think there may have been some mistake in the dosage they told you to give. Trazadone is usually dosed in 100mg pills and large dogs are given up to 200mg about 2 hours before the vet visit to calm him down. I would hesitate to give him more than that. I would start with 200mg and speak to your vet again to make sure the dosage they want to give him is actually 5 tablets and what their reasoning would be. It is important to give the drug enough time to work which usually peaks in about 2 hours so if you do that, 200mg should work fine. Good luck I hope this helps!

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    2Pet Parents found this answer helpful

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