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My shelter cat has URI, not improving. Is it an immune disease?

Updated On September 23rd, 2025

Pet's info: Cat | Oriental | Female | spayed | 3.4 lbs

New 2 yr cat from shelter was tested for felv/fib and was neg. She was given FVRCP, rabies vaccine, anti parisites and spayed. Came home with us and has been very sick with a uri for 5 weeks. Been to the vet 5 times. Won't eat, viral ulcers mouth, eyelid, nose. Fluids, an antiviral, 3 antibiotics, and eye ointment and she is no better. Could she have caught an immunosuppressive disease while there and should she be retested? How long for the vaccines to be actively protecting her? Suggestions?

1 Answer

Most Helpful Answer

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Answered By Megan, DVM, CVA

Veterinarian

Published on October 21st, 2017

Poor Sabina! If she has nasal discharge or coughing, you may inquire with your vet about doing a culture and sensitive on the nasal discharge or doing a trans-tracheal wash to see if she has a resistant bacteria. Also if she doesn't have a high white blood count then you may consider steroids if she doesn't have congestion. I would talk to your vet in depth about steroids as these can make an infection worse if it isn't an auto-immune problem. I would also get her on a lysine supplement like Viralys or vetriscience lysine chews for cats. You can also request vitamins B12 injections and an appetite stimulant to help with her appetite. If she has been a long time without eating, make sure she has had her chemistry ( liver and kidney) values check to ensure she isn't have liver or kidney issues. You could have her retested for FELV/FIV. If she was recently infected before adoption then it may not show up on a test yet. The vaccines usually take effect within 5-7 days of receiving them so she should be protected. I hope this helps and she starts to get better really soon!

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