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Distemper in my litter. Can I give 5-in-1 vaccines to other pups?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed | Female | 2 months and 4 days old | 7.7 lbs

Hi! I just dewormed my puppies 3 days ago. Right now one of the puppies has canine distemper and Im worried about the other puppies and their mom. Can I give them 5 in 1 vaccines? Or what is the right thing to do? I think oreo is slowing showing signs of distemper because of eye mucus

4 Answers

Most Helpful Answer

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Answered By Destini R. Holloway, DVM

Veterinarian

Published on October 19th, 2017

You can give any puppy a vaccine as long as their temperature is normal and they are not actively sick. However, you do run the risk of vaccinating a puppy who already has been exposed, but just hasn't had a full display of symptoms yet. This is an unfortunate situation to be in. Eye mucous is not a clear sign of distemper, but instead it would entail the full scope of the disease which is lethargy, not eating, fever, upper airway infection symptoms, etc. I would suggest getting a vet involved to do a full exam on these puppies first to determine which are not healthy enough for vaccination, and then try to isolate the sick ones to hopefully help prevent the entire litter from catching it. Hopefully you can save a few of these puppies. Treatment for distemiper is costly and very rarely will result in survival. It is just a terrible disease and I hope the best for your pups as they try to get through this. Best wishes and take care.

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Related Answers from Veterinarians

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    Answered By Ricardo Fernandez, DVM

    Veterinarian, Veterinary Oncology Resident

    Published on August 9th, 2019

    Thanks for using Petco Pet Education Center, formerly Petcoach! Possible side effects after vaccines include pain at the injection site, lethargy, diarrhea, inappetence and general discomfort. This should subside within 1-2 days. If it does not improve or it worsens, have Luns evaluated by a veterinarian for further assessment and treatment. Otherwise, Luns will likely start feeling better shortly. I do recommend going for the booster vaccine. Good luck and best wishes!

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    Answered By Destini R. Holloway, DVM

    Veterinarian

    Published on July 12th, 2017

    I would most certainly observe them first before giving a potentially sick pet a vaccine, which will challenge their immune system almost immediately. I sure hope your puppies are ok and do not have distemper, because there is no real reliable cure for that. Also I am not sure what serum test was performed exactly, so more specifics are needed in that regard. A distemper test has to be ran at an outside lab and takes several days for results. Some possibilities here are that they both have distemper or are both having an abnormal reaction to the vaccine. If your adult dogs are acting normal, then I would not concern yourself about them at the moment. Your focus should be on the puppies, since they are the only ones that are symptomatic.

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    Answered By Dr. Strydom, DVM

    Veterinarian

    Published on March 31st, 2018

    Hello, so sorry this happened. It sounds like distemper to me. At 10 weeks of age they likely only had one or two vaccinations. hat is not considered "all their shots". They are not fully vaccinated until they are 16 weeks old. In the meantime they are still susceptible to diseases like distemper. Unfortunately, there is no good testing for distemper. You usually diagnose by clinical signs. There are some tests that can be done but they are costly and the testing takes a long time. Here is an article about distemper. If I had to place a bet I would say this is the cause. ( http://www.veterinarypartner.com/Content.plx?P=A&S=0&C=0&A=1733 )

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