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My cats have chronic diarrhea, and one is acting strange. Help!

Updated On September 23rd, 2025

Pet's info: Cat | Domestic Longhair | Female | unspayed

I have 3 cats, 2 males and one female 1 of the males and the female are brother and sister and are about 6 months old. The other male is 2. They have been having diarrhea issues for a while now and have each been to the vet at least 3 times. We've done about 4 fecal tests on each, and treated them for coccidiosis and giardia. The diarrhea has continued and the female is having behaviour problems now (one minute she's cuddly, the next she's hissing at you, and then she hides under the couch

1 Answer

Most Helpful Answer

Published on September 30th, 2017

If these cats have not been on long-term medication like probiotics and metronidazole, I would start these. Also, all cats might benefit from a food-allergy diet trial like Hills z/d fed exclusively for 8-10 weeks. This helps to rule out food allergies as a cause for chronic diarrhea. If these things don't work, you may have to actually send out fecal tests for culture and sensitivity to have done at an outside laboratory as most vet clinics are only equipped to do basic parasite fecal floats and smears in-house. Your female who is having behavior issues may benefit from anti-anxiety medications like Zylkene or Lorazepam, or even an anti-depressant. Since all three are young cats, it's most likely that they are sharing a parasitic or other intestinal infection that is causing chronic diarrhea, so I think you are on the right tract to continue to monitor for coccidiosis and giardiasis. They may need much longer-term treatment to clear these kinds of infection. Hope that helps!

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