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Dog with Cushing's on Trilostane has seizures. Is Adrenal Harmony better?

Updated On September 23rd, 2025

Pet's info: Dog | Miniature Poodle | Female | spayed | 14 years and 1 month old | 12 lbs

Adrenal Harmony is advertised as a natural remedy. Can you speak to that? My 10 lb poodle has Cushings and we settled on 10mg of Trilostane...1/2 2x per day. She is 14 and I just thought she was showing signs of age. The meds perked her up but she seems to be having tiny seizures. She freezes and then it is as if she is having a cold chill, just shivers and seems to lose a little of her balance. Side effect of meds or symptom of Cushings? If side effect might this alternative be better?

1 Answer

Most Helpful Answer

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Answered By Susan England-Foster

Veterinarian

Published on September 23rd, 2017

Typically Cushing disease does not cause seizure like behavior. Also I have used trilostane often and have never seen seizures with the medicine. With a very old dog it is possible that Emma has started having seizures secondary to his age/brain function. I would recommend consulting you vet about possible a referral to a neurologist or even starting seizure medications if needed. You can try and video tape the episodes to help your vet determine what is actually going on. Hope that helps

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