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Is it safe to give my cat a flea tablet if Frontline isn't working?

Updated On September 23rd, 2025

Pet's info: Cat | Domestic Longhair | Female | spayed

Hi there, Is it possible to give my cats Johnsons 4fleas tablets as well as frontline spot on? The spot on runs out anyway on Saturday but has proven inaffective to this bout of fleas so was wondering if it would be safe to give them a tablet now or wait?

2 Answers

Most Helpful Answer

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Answered By Jessica Keay, DVM

Veterinarian

Published on September 19th, 2017

If the active ingredient is Nitenpyram (I am having trouble finding this product online but I believe this is the ingredient) then it is fine to give along with Frontline. If you are having a problem with fleas in your cat you may need a prescription product that works long term from your vet such as Comfortis in addition to treating your home, all other pets, and your yard. You can read more about flea control at http://www.veterinarypartner.com/Content.plx?P=A&S=0&C=0&A=1575 Always be sure you are using a product labeled for cats, as some flea products for dogs are toxic to cats.

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9Pet Parents found this answer helpful

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    Answered By Jennifer Summerfield, DVM CPDT-KA

    Veterinarian, Certified Dog Trainer

    Published on November 17th, 2017

    I personally don't recommend any over-the-counter flea sprays for cats, as they tend to not be very effective and many can be dangerous depending on the chemicals used. Cats are very sensitive! The best over-the-counter flea treatment available for cats is Advantage. Better options for fleas, which also prevent intestinal parasites and heartworm disease, are Advantage Multi (Advocate) or Revolution (Stronghold) - these are prescription medications you can get from your veterinarian, or order online with a prescription from the vet.

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