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Will fluconazole for dog paw yeast infection cause seizures or liver issues?

Updated On September 23rd, 2025

Pet's info: Dog | German Shepherd | Male | unneutered | 1 year old

Can FLUCONAZOLE 150 mg given to 34.8kg dog to treat yeast infection b/w paws can cause side effect like SEIZURES or any liver or kidney problem or any other problem that can be life threatening ??????

4 Answers

Most Helpful Answer

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Answered By Dr. Melanie, BVSc MS

Veterinarian

Published on November 28th, 2016

Fluconazole does not cause seizures. A reported side effect can be jaundice, which can be caused by liver failure, but overall it has been found to be a safe drug in dogs. It has the fewest adverse side effects compared with other anti-fungal drugs used for dogs.

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    Answered By Dr. Leigh, DVM

    Veterinarian

    Published on

    Your dog could have a reaction or side effect to any medication that he takes. Although the risk is usually low, there is always a risk of side effects when giving medications. If your dog is healthy than the risk is probably very low and the benefit of taking the drug for a yeast infection would outweigh the risks. If you are concerned, than you should talk to the vet who prescribed the medication but the likelihood of it causing a life threatening side effect is probably very low, especially if your dog is healthy.

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    Answered By Dr. Melanie, BVSc MS

    Veterinarian

    Published on November 28th, 2016

    Any drug has side effects, but fluconazole has fewer adverse side effects than other anti-fungal drugs prescribed for dogs. It is considered a safe drug. It does not cause seizures. Potential side effects can include vomiting, diarrhea, allergic reaction, loss of appetite, jaundice, or pale gums, tongue, and nose. As I said, any drug has side effects, and if you have any concerns about Bruno taking fluconazole, i would recommend giving the vet who prescribed it a call to discuss your concerns.

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    Answered By Lindsey Edwards MVB, BSc, IVCA

    Veterinarian

    Published on November 28th, 2016

    Severe side effects are very rare but can include vomiting and diarrhea, liver damage and skin rashes. As with all medications the benefits of treatment should be weighed up against any possible risks. You should discuss this with the prescribing vet if you are concerned

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