Dog's recurring bladder infection with pus, negative culture. What to do?

Question

My 2 1/2 yr old black lab pit mix has had a reoccurring infection with pus coming from his bladder. I went to see a nearby vet about 3 months ago and they gave him a 10 day release shot, however, it came back after two weeks. I repeated this twice, until i started him on oral antibiotics. He is now on his second round of pills and the problem isn't getting better. I did a culture test via my vet and it came up "no specific pathogens". Any thoughts of how to treat this infection finally?? Pet's info: Dog | Labrador Retriever | Male | neutered | 2 years and 6 months old | 69 lbs

Destini R. Holloway, DVM · Accepted Answer

I would highly recommend having an x-ray taken of your pets abdomens to rule out any potential bladder or kidney stones. If a stone is present this could explain the repeat infections. Also I find it very unusual to have pus in the urine but a negative culture. If Reagan was currently on antibiotics when the urine culture samples were taken this can lead to a false negative. I also would recommend bloodwork analysis to rule out a potential kidney involvement here. Pyonephritis can cause pus in the urine as well. In the meantime get Reagan on daily probiotics (Cultutelle over the counter works well, or Fortilfora) and fish oils (from your local pet store) which both have been proven helpful for repeat urinate issues.

Dog's recurring bladder infection with pus, negative culture. What to do?

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