Petco Text Logo
Petco Pet Logo

Can I give my dog Frontline while he is currently on Nexgard?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | 70 lbs

Can I give my dog frontline if he is currently taking nexgard

4 Answers

Most Helpful Answer

Image profile

Answered By Jenna Beyer, DVM, MBA, cVMA

Veterinarian, Certified Veterinary Acupuncturist

Published on August 31st, 2017

Yes, if you feel that you need additional flea protection, you can use a topical and an oral preventative at the same time. I do recommend that you separate them by 2 weeks. This is not because of toxic interactions but just to help overlap the coverage.

Vote icon

22Pet Parents found this answer helpful

Related Answers from Veterinarians

  • Image profile

    Answered By Angel Alvarado, LVT

    Licensed Veterinary Technician

    Published on August 2nd, 2015

    If you wait 3-5 days after using flea shampoo, you can probably use NexGard safely. I have always had success in treating fleas using Frontline Plus. Frontline is very effective when used properly. Use the appropriate dose based on your pet's weight. Do not split doses between pets. It must be applied at least 3 days before or after a bath or grooming. It must be applied directly to the skin. This is accomplished by parting the fur with the applicator tip down to the skin. Treat ALL pets in the house for at least 3 consecutive months. The environment must also be treated. Vacuum all areas and dispose of the bag outdoors. Wash all fabrics and beddings that have had contact with any pet in the hottest water temp allowable. Knockout Area treatment (by Virbac) is just one very effective product. Lastly, treat all pets for tapeworm since fleas carry the risk of tapeworm infection. If you purchased your Frontline from your vet, you can contact Merial at www.frontline.com and take advantage of their Guarantee.

    Vote icon

    12Pet Parents found this answer helpful

  • Image profile

    Answered By Dr. Strydom, DVM

    Veterinarian

    Published on October 12th, 2017

    It is better if you wait at least two weeks in between medications. Most of the tick and flea products manufacturers do not recommend using more than one preparation at the same time. It is hard to predict what side effects could develop if two similar products are used at the same time. If you want to call Nexguard's 800 number (should be on the box) and tell them what product you already applied they may tell you it's OK. Don't forget to treat the house and/or yard for fleas. This will help tremendously. I suggest Knockout Spray ES for the house and Advantage II yard spray. You can buy these online without a prescription. Also, don't forget to treat every pet in the household for fleas too!

    Vote icon

    1Pet Parents found this answer helpful

  • Image profile

    Answered By Andrea M. Brodie, DVM

    Veterinarian

    Published on October 30th, 2018

    You can give him the Nexgard now. There is more you can do: fleas only hop on the body of your pet when they want to feed, then they hop off again and stay in your pet's environment. So you need to treat all pets in the household as well as the environment (which contains the fleas, their eggs and larvae). Flea treatment:  1) Get some flea medication such as a Flea spray or a spot on from a pet shop or your veterinarian and apply monthly (Nexguard is great) 2) get flea powder, put some in your vacuum cleaner bag and vacuum your house and furniture and also non-carpeted areas frequently to remove flea larvae and eggs which live off house dust., Dispose of the bag in the trash outside. Hot-wash all the pet's bedding, If you do this diligently for a few months you will get rid of the fleas.

    Vote icon

    2Pet Parents found this answer helpful

See More Answers
image
Have A Vet Question?

Book an appointment with the pros – our expert vets are here to help.

Sponsored