How to help my dog's high bilirubin after plant toxicity exposure?

Question

My dog's bilirubin is at 20.7. We believe it's from ingesting leaves from a Jatropha tree. She's in Denamarin and was hospitalized with fluids for 5 days. Can you suggest anything to help get her bilirubin down? She's eating and drinking and is pretty much back to normal clinically but her bilirubin is a big concern. Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | spayed | 5 years and 7 months old | 58 lbs

Summer Walker, DVM, MS · Accepted Answer

Thank you for using Petco Pet Education Center, formerly Petcoach! When the liver suffers an insult (such as a toxicity) it can take some time for it to regenerate/repair and all values to return to normal. This process can take months. Typical supportive medications given to dogs with liver injury include Denamarin, Vitamin E, Acetylcysteine, and Ursodiol. A prescription hepatic diet (such as Hill's L/D or Royal Canin Hepatic) may also aid in decreasing any ongoing liver injury. Ursodiol is an oral medication, available by prescription only, that can add in reducing bilirubin by stimulating bile flow from the gallbladder through the biliary tree. It cannot be used if there is underlying gallbladder disorder, such as a gallbladder mucocele (gallstone). Your veterinarian will prescribe this if they feel this will benefit Tasha's recovery. You can certainly schedule a recheck with Tasha's veterinarian to discuss any additional medications or treatment options that may benefit her. The liver is a highly regenerative organ, and if given the proper support can make a complete or near-complete recovery.

How to help my dog's high bilirubin after plant toxicity exposure?

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