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My cat is acting strange on buprenorphine pain meds. What should I do?

Updated On September 23rd, 2025

Pet's info: Cat | Domestic Longhair | Male | neutered | 11.9 lbs

My cat is on pain medication. Buprenorphine 0.3 he is acting veri strange. He ask for food every two hours is being very quiet, hasn't used the bathroom, has not slept for the last 24 hrs

1 Answer

Most Helpful Answer

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Answered By Destini R. Holloway, DVM

Veterinarian

Published on August 18th, 2017

I am not sure how you are able to tell that he hasn't slept for 24 hrs unless you are also up yourself the entire time. Chances are he has slept somewhat, but these are still concerning symptoms that he may be having an adverse reaction to the medicaiton or that a lower dose is needed for him. Also it is concerning if he hasn't gone potty. Male neutered cats can get urinary blockages which causes them to be very vocal, lethargic and strain to urinate. I would advise taking him to your local vet right away for an evaluation and potentially stopping his medication until he is deemed healthy enough to proceed with either this medicaiton or an alternative. I hope that Cucho is able to make a full and speedy recovery. Best wishes and take care.

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