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My dog is sedated from buprenorphine for pancreatitis. Is it safe?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | spayed | 26 lbs

Our dog was given .3mg of buprenorphine for a very mild case of pancreatitis. She is heavily sedated and appears confused. how long will the sedation last andwill the drug have any negative impact on her pancreas? Also to note: she at no point exhibit any signs of lethargy due to pancreatitis. And did not exhibit any of the normal symptoms of pancreatitis aside from vomit with a small amount of blood. She weighs 25 pounds. And has been herself the whole time until the buprenorphine

1 Answer

Most Helpful Answer

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Answered By Jennifer Summerfield, DVM CPDT-KA

Veterinarian, Certified Dog Trainer

Published on August 12th, 2017

Buprenorphine often causes sedation as a side effect - sometimes a lot of sedation, as sounds like the case with Lady! The dose she received (0.3 mg for a 25 pound dog) is within the normal dosage range, and should not be expected to cause any serious problems at all :) The sedation should wear off in the next 6-8 hours, or possibly even sooner as the drug levels in her body start to drop. Buprenorphine has no negative impact on the pancreas at all, and is very commonly used for pain control in dogs with pancreatitis. I hope Lady starts to feel better soon!

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