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How much pancreatic enzyme should I give my puppy diagnosed with EPI?

Updated On September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Male | unneutered | 8 months and 6 days old | 88 lbs

Hi! Recently my vet diagnosed my puppy with insufficient pancreatic enzyme secretion and for that reason a high level of fat in the food is bad for him, but he told me that in general, this issue It resolves itself once he will adult. Now he eats puppy food and I give to him pancreatic enzyme twice a day. The dose is 200 mg of pancreatin (400 mg/day). I asked the vet exactly the dose and he doesn't know. How many mg I have to give to him per day? Thank you very much.

1 Answer

Most Helpful Answer

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Answered By Daniel Fonza, DVM

Veterinarian

Published on August 4th, 2017

Thank you for your post regarding Wally! I am sorry to hear that he has Exocrine Pancreatic Insufficiency. This can be managed and it sounds like your vet has you on the right path for treatment. However, I am not familiar with Pancreatin and I know that it is a human formulation. I would suggest switching to a veterinary-specific pancreatic powder such as Pancreved, Panakare or Pancrezyme. The doses for these are specifically labelled on each of the bottles. The origin of the enzymes in the veterinary-specific enzymatic powders are different from that of the human formulations, which is why I would encourage you to use one of the powders mentioned above. I hope this guides you in the right direction. Please do feel free to contact me with any further questions / concerns.

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