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How much MSM should I give my dog with hip dysplasia or joint pain?

Updated On September 23rd, 2025

Pet's info: Dog | Border Collie | Female | spayed | 14 years and 2 months old | 35 lbs

I have two dogs that are special needs. One is a 14 year old Border Collie with 3 legs. She had her left rear leg taken off at the hip 3 years ago. The other is a year old large mixed breed with hip dysplasia. I'm wondering if 1000 mg of MSM is to much. What would be the ideal mg?

1 Answer

Most Helpful Answer

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Answered By Dr. Strydom, DVM

Veterinarian

Published on July 28th, 2017

Hi there! Great question! I usually use 30 mg/kg/day or as close as I can get with the various capsule sizes. I would need their weights to give you an exact dose however you can figure it out easily with a simple calculation. For example: If Lilly weighs 40 pounds: 40 pounds/2.2 = 18.18kg 18.18kg x 30mg/kg = 545mg So, Lilly would need somewhere around 550mg per day. MSM isn't considered "toxic" but larger doses than can be absorbed can cause loose stools. If taken concomitantly with proven blood thinners (ie: aspirin therapy, heparin) there may be an accelerated blood thinning effect. Individuals with kidney problems or recurrent kidney stones should not take MSM. I hope this helps. Best wishes to you!

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