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My cat's kidney blood work is high after UTI. Is it kidney disease?

Updated On September 23rd, 2025

Pet's info: Cat | Domestic Shorthair | Male | neutered | 10 years and 6 months old | 19 lbs

Does a bun of 28 and a creatinine level of 2.6 means kidney disease in cats? My cat had a rough 5 weeks with cystitis and then a uti. He was on onsior, buprenorphine, started Prozac, and then antibiotics. Now after all that his blood work shows numbers listed above. Was this caused by meds and ciphlosporin antibiotics or do we now have kidney issues to deal with? For the record his normal for years was a creatinine of 2. Thanks.

1 Answer

Most Helpful Answer

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Answered By Jenny, DVM

Veterinarian

Published on July 24th, 2017

This does indicate kidney disease but not necessarily permanent. Cystitis can cause improper emptying of the bladder. If the bladder gets backed up, it affects the kidneys and can spread the infection there. Clearing the infection and getting the bladder emptying properly can resolve those values. You can switch him to a kidney diet and make sure he gets plenty of water. I would recheck the blood work in 1-2 weeks and see how the numbers compare. If they are worse, then you likely have kidney disease and he may benefit from IV or SQ fluids. If they improve, then it may have been a result of the cystitis and medicines

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