Updated On September 23rd, 2025
Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Male | neutered | 48 lbs
My dog has a blister on her toe which she licks constantly. Now she has blister between her toes. One digit is extremely swollen. Cellulitis? Also for the last two weeks she has been rubbing her face by her eyes on her paw. The skin around her eyes is inflammed. Could this be pemphigus ?
1 Answer
Published on July 16th, 2017
Hopefully Daisy has a less serious illness than pemphigus - typically we see interdigital cysts (blisters between toes) and sometimes blepharodermatitis (eyelid swelling) as symptoms of general allergic skin disease. Pemphigus is diagnosed with skin biopsies (taken surgically). I expect your vet may suggest a trial of an anti-allergy medicine like apoquel or possibly steroids to see if the problem resolves before a biopsy is needed. The vet may also suggest a food trial, and also other measures to control allergens.
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