Is human Metformin safe for pets? What are the dangers of giving it?

Question

Can we give 500mg of Metformin to a healthy 7 weeks old male ICR mice to induce lactic acidosis? this is regarding our research. Pet's info: Other | Unknown - Other | Male

Dr. Strydom, DVM · Accepted Answer

Hello. I am not sure what your researching but 500mg of Metformin is a normal dose for a human so I don't think it would be a good idea to give to a mouse. It would cause severe hypoglycemia and severe lactic acidosis. If your intention is for the mouse to live then I don't think it is a good idea. Maybe using a lower dose would be appropriate?

Is human Metformin safe for pets? What are the dangers of giving it?

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