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My senior dog has high liver enzymes. Is it medication or age?

Updated On September 23rd, 2025

My14 year old Jack Russel has cushing's disease when 7 years old.He been doing great on vetoryl.He got acute kidney and his results came back normal. He went on paradle for his arthritis for 3 weeks.He not on them now for one month and is doing great.The liver was high do you think vetoryl or paradle might of cause this?or old age?will his liver go back to normal?My dog is eating and seems happy.I just don`t want his liver to get worse and to prevent anymore damage.I appreciate your advice.

1 Answer

Most Helpful Answer

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Answered By Dr. Leigh, DVM

Veterinarian

Published on November 8th, 2016

Pardale is a non-steroidal anti-inflammatory medication that contains acetaminophen and codeine. Acetaminophen can cause liver toxicity in some dogs, especially if used inappropriately. Since he seems to be feeling better, there is a chance his liver will go back to normal with the discontinuation of the drug. Your vet could put him on a liver supplement, like Denamarin, to help his liver function better. Your vet can repeat bloodwork in a month to recheck his values. I would definitely be reluctant to put him back on a non-steroidal type medication for his arthritis or use one in very low doses. You could put him on a joint supplement, like Dasuquin and see if that help his joints.

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