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Why is my senior cat losing weight and vomiting with normal bloodwork?

Updated On September 23rd, 2025

Pet's info: Cat | Mixed Breed | Female | spayed | 16 years and 10 months old

hello, my calico cat is 16 years old. up to last year she weight 17 pounds and now she is down to 4.. accoriding to my veterinarian her blood work is normal, her lungs are clear, her hearth is good, no discharge from eyes or nose , no ear infection her thyroid is a bit low but he said it is only 2 points which is nothing much to be overly concern but will check again soon, she is on prescribe diet yet she vomits a lot.. any ideas or help will be appreciated very very much.. helen kotur

4 Answers

Most Helpful Answer

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Answered By Jennifer Summerfield, DVM CPDT-KA

Veterinarian, Certified Dog Trainer

Published on November 6th, 2016

Poor Checker! This is a huge amount of weight to have lost in a year, so I would say that something is definitely wrong. In older cats with significant weight loss like this and normal blood work, the most common possible causes would be an intestinal absorption issue like inflammatory bowel disease (which can be present even if she is not having diarrhea), or some type of abdominal cancer. The next diagnostic steps would be abdominal x-rays and ultrasound, with exploratory surgery and intestinal biopsies if needed to get a definite diagnosis. If this isn't possible for financial reasons, a trial course of oral steroids and injectable vitamin B12 might be helpful - I would suggest discussing these options with your vet to see what he/she recommends.

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    Answered By Jennifer Summerfield, DVM CPDT-KA

    Veterinarian, Certified Dog Trainer

    Published on February 6th, 2018

    Hi there! Yes, I would definitely suggest taking Harley to the vet for an exam and some lab work when you get a chance. It's common for cats to develop health issues as they get older, like chronic kidney disease or hyperthyroidism, that can cause appetite changes and weight loss as well as occasional vomiting. Some of these problems are very treatable with medication, so it's worth trying to get a diagnosis if you can. Your veterinarian should be able to advise you on what treatment options might be helpful depending on the results of his blood work.

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    Answered By Dr. Melanie, BVSc MS

    Veterinarian

    Published on November 25th, 2017

    Poor Piaf sounds very ill at the moment! It's quite concerning that she has no appetite for food and water, and this can quickly lead to a fatty liver (which cats develop when they don't eat for more than 72 hours) and dehydration. A fatty liver is fatal without treatment, so it needs to be avoided. It sounds like you have had some blood work done if she has very mildly elevated liver enzymes, but there may be something more going on with her such as cancer, which sometimes doesn't show up on blood work. I recommend further tests asap with the vet, such as x-rays and repeat blood work to start. She may also benefit from an appetitive stimulant and IV fluids to prevent dehydration. I would take her back into a vet immediately for treatment.

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  • Published on August 16th, 2017

    Poor Sarah! No this is not age-related, and she sounds quite ill. She needs to see a vet right away to get a diagnosis and come up with a treatment plan to get her feeling better. She needs to have bloodwork done, as well as abdominal xrays to start with. This will tell your vet if she has a metabolic disease going on like diabetes or hyperthyroidism, both of which are treatable. She may have an upper respiratory tract infection as well causing the breathing issues, and I suspect she needs to be on antibiotics and anti inflammatory medication to make her feel better. Hope that helps!

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