Why are my pitbull's skin abscesses getting worse on antibiotics?

Question

My 4 y/o pitbull began with what looked like a rash which has now developed into huge pus and blood-secreting abscesses. We have taken him to the vet but it only seems to get worse. First, he was given an injection and started on antibiotics. That didn't work. He is curently is on his third try with antibiotics: three pills Sulfamethoxazole every 12 hours for 14 days. He is depressed and only getting worse, I appreciate any help which can be given. Thanks. Pet's info: Dog | Pit Bull Terrier | Male | neutered | 5 years and 7 months old

Jennifer Summerfield, DVM CPDT-KA · Accepted Answer

Poor Buster! I'm sorry to hear that he's having so many problems. At this point, since he is on his third round of antibiotics without improvement, it sounds like he definitely needs some additional testing to help diagnose the problem. I would recommend a bacterial culture and sensitivity of the pus or discharge, as well as a punch biopsy of the skin to check for autoimmune diseases like lupus or pemphigus foliaceus. Depending on what else has been tried, other options might include a trial course of steroids or other immunosuppressive medication like Atopica or Apoquel, or a diet trial with a prescription hypoallergenic food. You can request referral to a veterinary dermatologist or get a second opinion from another vet locally if you feel that this is needed.

Why are my pitbull's skin abscesses getting worse on antibiotics?

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