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Can dogs take prednisone and Apoquel together for skin allergies?

Updated On September 23rd, 2025

Can my dog take prednisone and apoquel at the same time?

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Answered By Destini R. Holloway, DVM

Veterinarian

Published on August 2nd, 2016

Yes your pet sure can. Prednisone is a steroid and Apoquel is an immune modulator drug that specifically targets the receptors on your pets skin that cause itching. In fact, right now Apoquel has no drug interactions with any other type of medication, so it can be used along with just about anything. If your pet was not able to be maintained on Apoquel alone, then a low dose of prednisone or Cyclosporine can be used with it. Also I would recommend Fish oil supplements which are natural anti-inflammatory way to help a pet with skin allergies. Any pet formulated fish oil product from your local pet store will do.

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