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My dog is sick on Vetoryl for Cushing's. Are there alternatives?

Updated On September 23rd, 2025

Pet's info: Dog | Shih Tzu | Female | spayed | 16 years and 5 months old | 11 lbs

Is there anyone who knows if is a replacement or alternative medicine for vetoryl 30 mg. This medicine is making my dog very sick so I decided to stop it, As soon as I dld that I can tell she has more energy she eats better she is back been herself. But unfortunately I notice that the Cushing disease symptoms returned after a couple of days. Is there anyone who has a better sugestión. Thank you very much.

1 Answer

Most Helpful Answer

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Answered By Lauren M. Jones, VMD

Veterinarian

Published on June 29th, 2017

Vetoryl (trilostane) is the best medication for managing Cushing's disease, but I'm sorry to hear that Lacy has not been tolerating it well. I have anecdotally heard of some vets using a variety of supplements for managing Cushing's disease signs, but these supplements will not ultimately decrease the cortisol production by the adrenal glands and generally seem ineffective. I don't know how long Lacy was receiving Vetoryl, but some dogs can initially become lethargic, vomit, have diarrhea, or a decreased appetite. Fortunately, these signs typically resolve after a few days to a few weeks on the medication. It may be worth discussing a temporary dose adjustment with Lacy's vet to see if she tolerates a lower dose better before gradually increasing to her 30mg dose. Some dogs also benefit from supportive measures (anti nausea medications, bland diets, etc.) in the first few days to weeks of treatment. I hope this helps and that all goes well!

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