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Why is my dog sick after vaccine and antibiotics? Is it interference?

Updated On September 23rd, 2025

Pet's info: Dog | Beagle | Male | unneutered | 1 year and 2 months old | 26 lbs

can dog take antibiotics if he get a live vaccine.. he was sick. i took him to the vet they gave him simplicef and ear drops ..andnthe bortonela nose vaccine... then after days he gpt really sick.. im bot sure he it interfere between the shot and the medicines?

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1 Answer

Most Helpful Answer

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Answered By Megan, DVM, CVA

Veterinarian

Published on June 24th, 2017

Very rarely have I seen a dog get sick from the intranasal bordetella vaccine. If he is vomiting and/or having diarrhea then it is likely the simplecef that is causing this. I would make sure he is eating a full meal before giving him the antibiotics. If he is still sick or having other symptoms, I would contact you vet to ensure the antibiotics or ear drops wouldn't cause those symptoms. He may just need a different antibiotics that he can better tolerate. I hope this helps.

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