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Is a 45,000 WBC count dangerous for a dog with a uterine infection?

Updated On September 23rd, 2025

Pet's info: Dog | Miniature Schnauzer | Female | unspayed | 15 lbs

My brothers 6 yr old mini schnauzer has a WBC count of 45,000. She has a uterine infection post heat cycle and is receiving antibiotics and today a spay. That WBC seems awfully high. Is this a super dangerous level for a dog?

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2 Answers

Most Helpful Answer

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Answered By Sarah Box, BVSc

Veterinarian

Published on June 22nd, 2017

Poor Pickles! I am sorry to hear she has such a nasty infection! I am not surprised her WBC is elevated, this type of infection is usually very significant. It sounds like you have an excellent treatment plan in place however, as stabilization and surgery are the best way to treat. Be warned that recovery from a pyometra can be difficult, some dogs bounce back easily, others take longer and may need to stay in the hospital for a few days. I hope the surgery goes well and Pickles feels much better soon.

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    Answered By Dr. Rachel

    Veterinarian

    Published on

    A white blood cell count (WBC) of 45,000 is indeed high and does indicate a serious infection, but it is an appropriate response. White blood cells are mobilized into the bloodstream as part of the immune system's effort to fight off bacteria. If left untreated, an infected uterus (pyometra) can quickly cause dogs to become septic as the immune system becomes overwhelmed. It sounds like Pickles is in good hands - the best treatments for pyometra are antibiotics and spay as soon as possible. She is a cute dog - best of luck!

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