Updated On September 23rd, 2025
Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered
Can u use advantage II and a seresto collar on extra large dog at same time
1 Answer
Published on June 18th, 2017
It would not be recommended to do this, as a Seresto collar and Advantage II have the same active ingredients - so you would essentially be giving your dog a double dose of medication, which may not be safe. It shouldn't be necessary to use two different flea control medications as long as you are using an appropriate size/dose for your dog's weight. If you are already using one of these products and are finding that it is not effective, I would recommend switching to a different flea medication entirely, such as Nexgard or Bravecto - these are both much more effective in my experience.
6Pet Parents found this answer helpful
Book an appointment with the pros – our expert vets are here to help.