Updated On September 23rd, 2025
Pet's info: Dog | Mastiff | Male | unneutered | 140 lbs
Hi, We've taken our dog (english mastiff 1 year)to 2 different vets and they couldn't figure out what was wrong with him. His stomach is gurgling pretty much all day, he only eats select things (bland meat only), and after spending $4000 on a hospital stay the vets couldnt figure it out. Creatinine lvls last were 3.7 which were 5.8 in the beginning. BUN is now 36 and potassium is at 6.2 (down from 8.3). He still has diarrhea and is barely eating. I was hoping to get a second opinion. thank u
1 Answer
Published on June 14th, 2017
Levels of creatinine and BUN that are this high indicate a severe kidney disease also called acute renal failure. This can be caused by toxin ingestion e.g. ethylene glycol, infectious disease such as Leptosporosis, loss of blood flow to the kidneys, urine outflow blockage or even neoplasia (less likely given young age). Occasionally renal failure can also occur secondary to GI diseases such as pancreatitis - which would explain the diarrhea. If Simba is not in the hospital right now, he needs to be seen by a veterinarian for immediate medical care. Potassium levels this high could cause his heart to stop. Simba needs to have this potassium level treated immediately and needs to be on aggressive fluid therapy for the kidney disease. Make sure your veterinarian has ruled out all of the possible differentials discussed above. I would also recommend a consult with a boarded internal medicine specialist. You can find one in your area on www.acvim.org.
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