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My dog is restless, panting, whining after buprenorphine. What to do?

Updated On September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Female | spayed | 12 years and 7 months old

Emergency vet gave buprenorphine for hind leg pain an hour ago. Dog still very restless, wandering around, staring at walls, panting heavily, whining. It's very late. What should we do?

1 Answer

Most Helpful Answer

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Answered By Lauren Celestin, DVM

Veterinarian, Veterinary Dentistry Resident

Published on June 9th, 2017

Poor Sierra! I am sorry to hear that she is not feeling well. It sounds as if Sierra may be reacting to the Buprenorphine, which can cause restlessness and other nervous behaviors like the ones you have mentioned in some dogs and cats. Unfortunately, the only thing that can be done at home is trying to ease her anxiety. Sometimes, keeping it dark and quiet can help them settle. I would definitely recommend contacting the vet that saw her to discuss the possibility of a different pain medication. If Sierra shows no improvement or worsens within 12-24 hours, she should be reevaluated as soon as possible. I hope Sierra is able to get comfortable soon. Hang in there!

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