Dog has blood in urine, thick bladder, culture negative. Is it infection or cancer?

Question

Hello, 1 year old male dog ultrasound showed bladder wall thickening, has blood in urine. Urine culture negative for bacteria. Vet's next step is tissue biopsy. Do bacterial infections always show in cultures? Is the only remaining diagnosis cancer? Pet's info: Dog | Pug | Male | neutered | 1 year and 8 months old | 20 lbs

Dr. Massimo Orioles, DVM, Cert AVP, MRCVS · Accepted Answer

I would recommend to treat medically before doing any invasive procedure such as tissue biopsy. Inflammatory type of cystitis are common and bladder wall can be often thicker than normal (I should see the ultrasound images though to give you an opinion on that). mAnti-inflammatory medications (i would associate an antibiotic anyway even with negative culture) can be tried before deciding any invasive test. Please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further.

Dog has blood in urine, thick bladder, culture negative. Is it infection or cancer?

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