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My new cat has URI symptoms after distemper vaccine. Reaction?

Updated On September 23rd, 2025

Pet's info: Cat | Mixed Breed | Female | spayed | 9 years and 5 months old | 4.7 lbs

I recently adopted a cat who got a distemper vaccine on adoption day. She is now sick with an upper respiratory infection. Her mucus is yellow and she keeps sneezing and is very stuffed up. Could this be a reaction to the vaccine?

1 Answer

Most Helpful Answer

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Answered By Destini R. Holloway, DVM

Veterinarian

Published on May 28th, 2017

It is unlikely that she is sick from the vaccine (this rarely happens especially with killed vaccines), but instead she was exposed to a virus that she has not been protected against. Also if she were recently vaccinated (within the past couple of days), then it is likely she was exposed to a virus before her vaccine was give enough time to stimulate the proper immune response (typically takes 7 days for this to happen). At any rate, your sweet girl Daffy needs a short course of antibiotics prescribed by your vet to take care of her current upper respiratory infection and get her well again. I would recommend taking her in to he vet by tomorrow. I hope Daffy gets well soon. Best wishes.

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