Why are my senior cat's weak back legs worsening on gabapentin?

Question

I have a 17 yr old male cat that is having a very hard time with his back legs . They seem to be very weak and not painful . The vet put him on gabapentin but it isn't doing him any good . He just seems to be getting worse. I had a series of bloodwork done and it showed very early onset of kidney disease . What could possibly be causing his problem ? I am just beside myself with worry . Pet's info: Cat | Mixed Breed | Male | neutered | 17 years old | 12 lbs

Dr. Melanie, BVSc MS · Accepted Answer

I'm so sorry Pico isn't doing well! There could be a couple of things causing this, including the gabapentin. As cats age, their efficiency at metabolizing gabapentin can wane, and this can lead to hind limb weakness. That may be why he's getting worse. I would take him into the vet first thing tomorrow to discuss lowering the dose, which may help with the increasing hindlimb weakness. You can also discuss if using another medication in combination with the gabapentin is ideal for Pico.

Why are my senior cat's weak back legs worsening on gabapentin?

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