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My cat has FHS. Is Zylkene safe or are there other calming options?

Updated On September 23rd, 2025

Pet's info: Cat | American Shorthair | Female | spayed | 7 lbs

Hello, My cat has Feline Hyperesthesia Syndrome. I've looked into several OTC products that might help with keeping her calm and reducing the episodes. I've seen Zylkene recommended by several pet owners and pet shops such as Petco, PetSmart and Chewy. Is it a safe product? Is there another viable option or options?

1 Answer

Most Helpful Answer

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Answered By Jennifer Summerfield, DVM CPDT-KA

Veterinarian, Certified Dog Trainer

Published on May 6th, 2017

Yes, Zylkene is a very safe product if you want to try it with opal - it's made from milk proteins, and does not contain drugs of any kind. In my experience, it can certainly be helpful in promoting relaxation and relieving stress in some cats. I'm not sure whether this will help her feline hyperesthesia syndrome or not, as most of the time prescription medication like gabapentin or prednisolone is required to treat this problem effectively, but there should be no problem at all with giving it a try :)

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